منابع مشابه
hepatitis-associated aplastic anemia
there is a well-recognized relationship between aplastic anemia and viral hepatitis. clinically apparent hepatitis precedes aplastic anemia by a period of weeks to months. hepatitis is an infrequent cause of aplastic anemia and is usually severe and fatal if untreated. the clinical features and, particularly the response to immunosuppressive therapy strongly suggest that immune mechanisms media...
متن کاملHepatitis-associated aplastic anemia: successful outcome following immunosuppressive therapy.
Hepatitis-associated aplastic anemia is an uncommon variant seen in young, previously healthy individuals. The pancytopenia follows hepatitis by a few weeks and is usually severe and prolonged. Bone marrow transplantation remains the cornerstone of therapy. However, immunosuppressive therapy has been found to be effective. We report an 8-year-old girl who had non-A, B, C and E hepatitis-associa...
متن کاملAnalysis of T-cell repertoire in hepatitis-associated aplastic anemia.
Hepatitis-associated aplastic anemia (HAA) is a syndrome of bone marrow failure following an acute attack of seronegative hepatitis. Clinical features and liver histology suggest a central role for an immune-mediated mechanism. To characterize the immune response, we investigated the T-cell repertoire (T-cell receptor [TCR] V(beta) chain subfamily) of intrahepatic lymphocytes in HAA patients by...
متن کاملSevere Aplastic Anemia following Parvovirus B19-Associated Acute Hepatitis
Human parvovirus (HPV) B19 is linked to a variety of clinical manifestations, such as erythema infectiosum, nonimmune hydrops fetalis, and transient aplastic anemia. Although a few cases have shown HPVB19 infection as a possible causative agent for hepatitis-associated aplastic anemia (HAAA) in immunocompetent patients, most reported cases of HAAA following transient hepatitis did not have dela...
متن کاملAplastic anemia associated with pregnancy.
Aplastic anemia is not an uncommon disorder. Estimated frequency is 3-6 per million populations per year. Occurrence of aplastic anemia however, concurrently with pregnancy in a previously healthy woman is a rare phenomenon. Since 1888 when it was first described not more than a handful of cases have been reported in literature. Pregnancy associated with marrow aplasia poses great problems for ...
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ژورنال
عنوان ژورنال: Hematology/Oncology and Stem Cell Therapy
سال: 2020
ISSN: 1658-3876
DOI: 10.1016/j.hemonc.2020.10.001